Recent advances in the pathogenesis and drug actions in periodic paralyses and related channelophaties
The periodic paralysis(PP) are rare autosomal-dominant disorders associated to mutations in the skeletal muscle sodium, calcium and potassium channel genes characterized by muscle fiber depolarization with un-excitability, episodes of weakness with variations in serum potassium concentrations.Recent advances in thyrotoxic-PP(TPP) and hypokalemic-PP